The D2d Story
FEBRUARY 08, 2017
D2d enrolls last participant
The 2,423rd and last participant enrolls in D2d. Congratulations to the amazing staff for recruiting a wonderful group of dedicated participants.
DECEMBER 16, 2016
D2d enrolls 2,382nd participant
A participant from the Atlanta site was the 2,382nd participant enrolled in D2d. The study’s recruitment goal is achieved.
SEPTEMBER 25, 2016
D2d Annual Meeting
The D2d Study held its fourth Annual Meeting in Arlington, VA.
JUNE 27, 2016
D2d enrolls 2,000th participant
A participant from the Nebraska site was the 2,000th participant enrolled in the D2d study. Click here to find out more about the Nebraska site.
NOVEMBER 20, 2015
D2d enrolls 1,500th participant
A participant from the Florida site was the 1,500th participant enrolled in the D2d Study. Click here to find out more about the Florida site.
APRIL 20, 2015
D2d enrolls 1,000th participant
A participant from the MedStar site was the 1,000th participant enrolled in the D2d Study. Click here to find out more about the MedStar site.
NOVEMBER 17, 2014
D2d Annual Meeting
The second Annual Meeting was held in Crystal City, MD. Click here to see photos from the meeting
D2d enrolls 500th participant
The 500th participant enrolled in the D2d Study.
OCTOBER 15, 2013
D2d sites across are prescreening for people at risk for diabetes (i.e. pre-diabetes) to join D2d.
SEPTEMBER 19, 2013
First NIDDK supported trial to use IRBShare
D2d is the first NIDDK-supported trial and only the fifth NIH-supported study to join the IRBShare pilot phase.
JULY 9-10, 2013
Investigators Kick-off meeting
The first Investigators’ Meeting is held in Bethesda, MD. D2d investigators and coordinators worked together to plan a successful study launch.
June 1, 2013
U01 cooperative agreement grant awarded
Tufts Medical Center receives the UO1 cooperative agreement grant, supported by NIDDK and ODS, to conduct D2d.
May 31, 2013
DSMB inaugural meeting
The first Data Safety Monitoring Board meeting takes place in Bethesda, MD.
Association between vitamin D and Diabetes Risk in the Diabetes Prevention Program, 2012
Observational studies in the Nurses Health Study.
SEPTEMBER 14, 2012
U01 cooperative agreement grant reviewed
Tufts Medical Center’s U01 grant application undergoes scientific peer review by NIH Special Emphasis Study Section.
JUNE 5, 2012
U01 cooperative agreement grant submitted
Tufts Medical Center submits a 1,140 page U01 cooperative agreement grant to NIH for funding to conduct D2d.
MARCH 30, 2012
Progress of U34 planning phase reviewed
NIDDK External Evaluation Committee reviews the progress of the U34 planning phase and recommends to proceed with U01 grant application.
JULY 20, 2011
U34 implementation grant awarded
Tufts Medical Center is awarded a NIDDK-supported U34 planning grant, which provides support, NIH programmatic involvement, and technical assistance for the planning of D2d.
JULY 30, 2010
U34 implementation grant submitted
Tufts Medical Center submits a U34 planning grant to NIH for supporting the activities to establish a research team, tools for data management and study design of D2d.
JULY 1, 2010
NIDDK allows submission of implementation grant application
Tufts Medical Center receives approval for the submission of a U34 planning grant for D2d.
NIDDK Preliminary Review of D2d
NIDDK Large Studies Committee reviews preliminary concept of the D2d study.
Association between vitamin D and Diabetes Risk in Nurses Health Study, 2010
Observational studies in Nurses Health Study strongly support an association between vitamin D concentration and incident diabetes.
NIDDK Large Studies Committee reviews preliminary concept of D2d, 2009-2010
The preliminary concept of D2d goes through multiple internal reviews by NIDDK.
The NIDDK/ODS-supported Calcium and Vitamin D and Diabetes Mellitus (CaDDM) trial starts in 2006. Results support a mechanistic link between vitamin D and diabetes risk.
Idea is conceived, July 2002
Idea that vitamin D may be linked to type 2 diabetes is conceived.