The D2d Story

D2d enrolls 2,000th participant

A participant from the Nebraska site was the 2,000th participant enrolled in the D2d study. Click here to find out more about the Nebraska site.

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D2d enrolls 1,500th participant

A participant from the Florida site was the 1,500th participant enrolled in the D2d Study. Click here to find out more about the Florida site.

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D2d Annual Meeting

The D2d Study held its third Annual Meeting in Arlington, VA. Click here to see photos from this year’s meeting.

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D2d enrolls 1,000th participant

A participant from the MedStar site was the 1,000th participant enrolled in the D2d Study. Click here to find out more about the MedStar site.

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D2d Annual Meeting

The second Annual Meeting was held in Crystal City, MD. Click here to see photos from the meeting

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First D2d Publication

Rationale and Design of the Vitamin D and Type 2 Diabetes (D2d) Study: A Diabetes Prevention Trial – click here to read article

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D2d enrolls 500th participant

The 500th participant enrolled in the D2d Study.

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Recruitment begins

D2d sites across are prescreening for people at risk for diabetes (i.e. pre-diabetes) to join D2d. For recruitment activity near you, please click here.

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First NIDDK supported trial to use IRBShare

D2d is the first NIDDK-supported trial and only the fifth NIH-supported study to join the IRBShare pilot phase.

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Investigators Kick-off meeting

The first Investigators’ Meeting is held in Bethesda, MD. D2d investigators and coordinators worked together to plan a successful study launch.

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DSMB inaugural meeting

The first Data Safety Monitoring Board meeting takes place in Bethesda, MD.

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U01 cooperative agreement grant awarded

Tufts Medical Center receives the UO1 cooperative agreement grant, supported by NIDDK and ODS, to conduct D2d.

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U01 cooperative agreement grant reviewed

Tufts Medical Center’s U01 grant application undergoes scientific peer review by NIH Special Emphasis Study Section.

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U01 cooperative agreement grant submitted

Tufts Medical Center submits a 1,140 page U01 cooperative agreement grant to NIH for funding to conduct D2d.

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Progress of U34 planning phase reviewed

NIDDK External Evaluation Committee reviews the progress of the U34 planning phase and recommends to proceed with U01 grant application.

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U34 implementation grant awarded

Tufts Medical Center is awarded a NIDDK-supported U34 planning grant, which provides support, NIH programmatic involvement, and technical assistance for the planning of D2d.

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U34 implementation grant submitted

Tufts Medical Center submits a U34 planning grant to NIH for supporting the activities to establish a research team, tools for data management and study design of D2d.

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NIDDK allows submission of implementation grant application

Tufts Medical Center receives approval for the submission of a U34 planning grant for D2d.

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NIDDK Preliminary Review of D2d

NIDDK Large Studies Committee reviews preliminary concept of the D2d study.

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R01 grant

NIDDK/ODS-supported R01 grant for the Calcium & Vitamin D and Diabetes Mellitus (CaDDM) trial is awarded to Tufts Medical Center.

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